Arab Today, arab today scientists use artemisia annua plant to produce breast cancer drugs
Last Updated : GMT 22:15:37
Arab Today, arab today
Arab Today, arab today

Scientists use Artemisia annua plant to produce breast cancer drugs

Arab Today, arab today

Arab Today, arab today Scientists use Artemisia annua plant to produce breast cancer drugs

Artemisia annua plant
Tehran - FNA

Iranian researchers produced anti-breast-cancer drug by using Artemisia annua plant.

The drug has been produced and analyzed at laboratorial scale, and it has successful effects in reducing the size of breast cancer tumors in animal samples.

Artemisinin is the active pharmaceutical ingredient (API) of Artemisia annua plant. Artemisinin has more toxicity on cancer cells in the presence of iron and transferrin. In this research, targeted magnetic nanoliposomes containing artemisinin and holo-transferrin were produced and in-vitro studies were carried out on their anticancer effect on breast cancer cells (MCF-7). In-vivo studies were also carried out on mice suffering from breast cancer.

Based on the results, the functionalization of nanoliposomes with magnetic iron nanoparticles facilitates drug delivery to the tumors. In addition, a significant increase is observed in the efficiency of the entrapped drug in the elimination of breast tumor in the sample animals.

According to the researchers, magnetic nanoliposomes containing artemisinin and transferrin were produced in this research through extrusion method, and some of their physical and chemical properties were studied. Next, in-vitro studies were carried out on the toxicity of the produced nanoliposomes through MTT method on MCF-7 cancer cells.

Results showed that the amount of artemisinin and transferrin in the tumor increased 10 and 5.5 times respectively in comparison with the complex created with the free form of the drugs two hours after the injection of magnetic nanoliposomes containing medication in the presence of magnetic field. In addition, the tumor volume in the sample mice significantly reduced in 15 days due to the presence of the magnetic field.

Results of the research have been published in PHARMACOGNOSY MAGAZINE, vol. 11, issue 42, 2015, pp. 117-122.

arabstoday
arabstoday

Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

Arab Today, arab today scientists use artemisia annua plant to produce breast cancer drugs Arab Today, arab today scientists use artemisia annua plant to produce breast cancer drugs

 



Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

Arab Today, arab today scientists use artemisia annua plant to produce breast cancer drugs Arab Today, arab today scientists use artemisia annua plant to produce breast cancer drugs

 



Arab Today, arab today
Arab Today, arab today Youssra depended on colored foam

GMT 16:53 2017 Tuesday ,05 September

Youssra depended on colored foam
Arab Today, arab today O'Leary: Could ground more planes

GMT 06:49 2017 Friday ,22 September

O'Leary: Could ground more planes
Arab Today, arab today Etiquette expert underlines importance of gifts

GMT 17:52 2017 Sunday ,03 September

Etiquette expert underlines importance of gifts
Arab Today, arab today Huthis stage defiant rally 3 years

GMT 05:29 2017 Friday ,22 September

Huthis stage defiant rally 3 years
Arab Today, arab today Saudi Arabia to unblock internet calling apps

GMT 11:31 2017 Wednesday ,20 September

Saudi Arabia to unblock internet calling apps
Arab Today, arab today
Arab Today, arab today
Arab Today, arab today Ministry seeks to improve education

GMT 14:49 2017 Sunday ,17 September

Ministry seeks to improve education
Arab Today, arab today All eyes on May as she prepares

GMT 10:16 2017 Friday ,22 September

All eyes on May as she prepares
Arab Today, arab today Puerto Rico, Virgin Islands brace

GMT 12:01 2017 Wednesday ,20 September

Puerto Rico, Virgin Islands brace
Arab Today, arab today The history of solar eclipses

GMT 05:16 2017 Sunday ,20 August

The history of solar eclipses
Arab Today, arab today Mercedes pumps 1 bln euros    

GMT 06:04 2017 Friday ,22 September

Mercedes pumps 1 bln euros    
Arab Today, arab today Intel chips loaded in Waymo

GMT 14:43 2017 Wednesday ,20 September

Intel chips loaded in Waymo
Arab Today, arab today Youssra prepares for launching her  program

GMT 08:59 2017 Wednesday ,20 September

Youssra prepares for launching her program
Arab Today, arab today France hopeful of persuading Trump

GMT 06:21 2017 Wednesday ,20 September

France hopeful of persuading Trump

GMT 09:40 2017 Tuesday ,19 September

Actress Ream Hhagag prepares for a new film

GMT 18:09 2017 Thursday ,21 September

China lifts 10-year travel ban

GMT 16:53 2017 Saturday ,02 September

Mai importance of gifts during Eid Al-Adha

GMT 19:18 2017 Monday ,18 September

5,000 'Dieselgate' deaths in Europe per year

GMT 10:46 2017 Saturday ,05 August

Nanis reveals simple ideas for home renovation

GMT 18:03 2017 Thursday ,21 September

Alarm over flesh-eating ulcer cases

GMT 07:00 2017 Wednesday ,20 September

A no-frills business success

GMT 17:12 2017 Monday ,07 August

Al-Shawaifi reveals secrets of total solar eclipse

GMT 12:46 2017 Thursday ,21 September

Google likely to buy stake in Taiwan smartphone maker HTC

GMT 11:37 2017 Saturday ,12 August

Fashion designer reveals her new collection
Arab Today, arab today
Arab Today, arab today
 
 Arab Today Facebook,arab today facebook  Arab Today Twitter,arab today twitter Arab Today Rss,arab today rss  Arab Today Youtube,arab today youtube  Arab Today Youtube,arab today youtube
arabstoday arabstoday arabstoday arabstoday
arabstoday arabstoday arabstoday
arabstoday
بناية النخيل - رأس النبع _ خلف السفارة الفرنسية _بيروت - لبنان
arabstoday, Arabstoday, Arabstoday