geneediting technique heals mice with muscular dystrophy
Last Updated : GMT 06:49:16
Arab Today, arab today
Arab Today, arab today
Last Updated : GMT 06:49:16
Arab Today, arab today

Gene-editing technique heals mice with muscular dystrophy

Arab Today, arab today

Arab Today, arab today Gene-editing technique heals mice with muscular dystrophy

Duke University researchers reported December 31 in the journal Science
Washington - AFP

Researchers have succeeded for the first time in reversing a degenerative illness in mice, using a revolutionary gene-editing technique that one day may help cure similar diseases in humans.
Three studies published Thursday in the journal Science said researchers employed a technique known as CRISPR -- clustered regularly interspaced short palindromic repeats -- to cure an adult mouse model suffering Duchenne muscular dystrophy, a disorder that affects one in every 5,000 baby boys.

"This marks the first time that CRISPR has successfully treated a genetic disease inside a fully developed living mammal with a strategy that has the potential to be translated to human therapy," researchers said.

Duchenne muscular dystrophy causes progressive weakness because of genetic mutations that interfere with the production of dystrophin, a protein needed to form healthy muscle.

The novel gene-editing technique fixes mutations that cause genetic diseases by making precise changes to the DNA of the ailing subject, using non-pathogenic viruses as delivery vehicles for the modified genes.

Charles Gersbach, associate professor of biomedical engineering at Duke University and the leading scientist on one of the studies, recently began focusing on CRISPR/Cas9 -- a modified version of a bacterial defense system that targets and slices apart the DNA of familiar invading viruses.

After refining the technique, Gersbach and his team first delivered the therapy directly to a leg muscle in an adult mouse, resulting in an increase in muscle strength as well as some correction of muscles throughout the body, including in the heart.

"There is still a significant amount of work to do to translate this to a human therapy and demonstrate safety," Gersbach cautioned.

"But these results coming from our first experiments are very exciting."

 

arabstoday
arabstoday
0

Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

geneediting technique heals mice with muscular dystrophy geneediting technique heals mice with muscular dystrophy

 



Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

geneediting technique heals mice with muscular dystrophy geneediting technique heals mice with muscular dystrophy

 



GMT 18:15 2017 Sunday ,17 September

Inter Milan stay top, Roma on the move in Serie A

GMT 12:47 2015 Sunday ,18 October

UAE Committed to achieving global food security

GMT 08:19 2017 Thursday ,19 January

Nigeria announces deployment of troops to Gambia

GMT 12:57 2017 Wednesday ,27 September

Bahrain Bourse daily trading performance

GMT 15:58 2017 Tuesday ,28 March

Israeli Police Arrest 11 Al-Aqsa Guards

GMT 03:25 2017 Friday ,15 September

July24th-August23rd

GMT 07:26 2017 Thursday ,07 September

Fashion spotlight CENTRESTAGE opens in Hong Kong

GMT 21:27 2015 Monday ,06 July

Tunisia beach gunman had worked in tourism

GMT 10:25 2017 Saturday ,15 April

Sock avoids upset to reach Houston semis

GMT 08:33 2017 Saturday ,29 April

Turkish authorities block access to Wikipedia

GMT 16:33 2017 Tuesday ,05 September

MP calls for private sector participate

GMT 12:22 2015 Saturday ,26 September

New Era announces London flagship launch

GMT 11:42 2017 Saturday ,25 November

Sydney in multi-billion-dollar stadium splurge
Arab Today, arab today
 
 Arab Today Facebook,arab today facebook  Arab Today Twitter,arab today twitter Arab Today Rss,arab today rss  Arab Today Youtube,arab today youtube  Arab Today Youtube,arab today youtube

Maintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2021 ©

Maintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2021 ©

arabstoday arabstoday arabstoday arabstoday
arabstoday arabstoday arabstoday
arabstoday
بناية النخيل - رأس النبع _ خلف السفارة الفرنسية _بيروت - لبنان
arabstoday, Arabstoday, Arabstoday