Arab Today, arab today statins dont cause muscle pain
Last Updated : GMT 06:53:52
Arab Today, arab today
Arab Today, arab today

At a psychological phenomenon 'nocebo'

Statins Don't Cause Muscle Pain

Arab Today, arab today

Arab Today, arab today Statins Don't Cause Muscle Pain

Cholesterol-lowering statin drugs
London - Arab Today

Cholesterol-lowering statin drugs may have been wrongly blamed for muscle pain and weakness, said a study Wednesday that pointed the finger at a psychological phenomenon called the "nocebo" effect.

It happens when people suffer side-effects because they expect to -- the opposite of the "placebo" effect when a patient gets better on a dummy drug they believe to be the real thing.

"Patients can experience very real pain as a result of the nocebo effect and the expectation that drugs will cause harm," said Peter Sever of Imperial College London, the lead author of a study published in The Lancet medical journal.

In this case, multiple reports of alleged side-effects from statins appear to have convinced people to experience them -- and prompted many to stop taking the drug.

A large-scale quitting of statins is estimated to have resulted in "thousands of fatal and disabling heart attacks and strokes, which would otherwise have been avoided," wrote the research team.

"Seldom in the history of modern therapeutics have the substantial proven benefits of a treatment been compromised to such an extent by serious misrepresentations of the evidence for its safety."

Statins are prescribed to lower cholesterol in people at high risk of heart attack or a stroke. 

Known side effects include an increased diabetes risk, the study said. But muscle pain and weakness has remained contentious, with some studies finding a link, and others none.

The latest study offers an explanation for the apparent contradiction.

- Benefits outweigh risks -Data gathered from about 10,000 people in Britain, Ireland and Scandinavia between 1998 and 2004, showed that patients who did not know they were given a statin in a drug trial did not report significantly more muscle complaints.

It is only when they were told they were taking a statin that people started complaining of muscle ailments -- 41 percent more compared to those not taking the drug.

The muscle symptoms thus appeared "unlikely to be due to the drug itself", Sever told AFP.

"Just as the placebo effect can be very strong, so too can the nocebo effect."

The researchers also found no evidence for a heightened risk of erectile dysfunction or sleep disturbance from statin use.

"We hope that patients will understand this and be prepared to take the statin," said Sever.

"The problem is that patients and doctors are not prescribing statins or patients are not taking them for fear of side effects. They need to weigh up the benefit of the statins and the risks. The latter are minimal."

Amitava Banerjee of University College London, an expert in drug trial analysis, said the study showed that "muscle pain is very common, but far less commonly caused by statins."

"If you are at high risk of cardiovascular disease or have had a heart attack or stroke and a statin is recommended, fear of muscle-related side effects alone should not prevent you taking a statin," Banerjee, who was not involved in the study, commented via the Science Media Centre in London.

One limitation of the study was that it considered a single statin, atorvastatin.

The trial was funded by Pfizer, which markets atorvastatin under the trade name Lipitor.

arabstoday
arabstoday

GMT 08:54 2017 Friday ,05 May

As House passes Obamacare repeal

GMT 07:40 2017 Thursday ,04 May

Food imports at all-time low

GMT 09:57 2017 Wednesday ,03 May

Statins Don't Cause Muscle Pain

GMT 14:38 2017 Tuesday ,02 May

1.4m Children Acutely Malnourished

GMT 14:42 2017 Monday ,01 May

Mobile Clinics Deliver Precious Medical Care

GMT 12:30 2017 Saturday ,29 April

Italian Woman Returns Mixed-Race Baby

GMT 10:13 2017 Friday ,28 April

carries out last execution

GMT 10:05 2017 Thursday ,27 April

Jeddah festival celebrates coffee, chocolate
View News in Arabic - Health: رئيسي ثان
Arab Today, arab today
Arab Today, arab today

Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

Arab Today, arab today statins dont cause muscle pain Arab Today, arab today statins dont cause muscle pain

 



Arab Today, arab today

Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

Arab Today, arab today statins dont cause muscle pain Arab Today, arab today statins dont cause muscle pain

 



Arab Today, arab today France defies terrorism through tourism

GMT 15:18 2017 Saturday ,20 May

France defies terrorism through tourism
Arab Today, arab today Zainab Fadel Oglu designs “Shakerin” mosque

GMT 12:13 2017 Thursday ,11 May

Zainab Fadel Oglu designs “Shakerin” mosque
Arab Today, arab today Seeks to move past rift with Israel

GMT 08:00 2017 Monday ,08 May

Seeks to move past rift with Israel
Arab Today, arab today Saudi Arabia ranks first in Ramadan tourism

GMT 15:54 2017 Wednesday ,17 May

Saudi Arabia ranks first in Ramadan tourism
Arab Today, arab today Wallpaper gives an extra glamour to the house

GMT 15:22 2017 Saturday ,06 May

Wallpaper gives an extra glamour to the house

GMT 08:54 2017 Friday ,05 May

As House passes Obamacare repeal

GMT 07:40 2017 Thursday ,04 May

Food imports at all-time low

GMT 09:57 2017 Wednesday ,03 May

Statins Don't Cause Muscle Pain

GMT 14:38 2017 Tuesday ,02 May

1.4m Children Acutely Malnourished

GMT 14:42 2017 Monday ,01 May

Mobile Clinics Deliver Precious Medical Care

GMT 12:30 2017 Saturday ,29 April

Italian Woman Returns Mixed-Race Baby

GMT 10:13 2017 Friday ,28 April

carries out last execution

GMT 10:05 2017 Thursday ,27 April

Jeddah festival celebrates coffee, chocolate
View News in Arabic - Health: رئيسي ثان
Arab Today, arab today
Arab Today, arab today

GMT 09:49 2017 Tuesday ,02 May

Girl barred from Malaysia chess competition

GMT 16:35 2017 Monday ,24 April

Oprah Winfrey conquers acting fears

GMT 10:26 2017 Friday ,05 May

Fishing with guns on a lake under threat

GMT 12:09 2017 Thursday ,04 May

Wild dolphins are sicker than captive ones

GMT 11:10 2017 Sunday ,30 April

Drawing on glass means happiness for me

GMT 14:30 2017 Thursday ,18 May

“Smile” is the weapon of positive persons

GMT 09:32 2017 Monday ,08 May

Trump's travel ban faces new test

GMT 06:31 2015 Thursday ,04 June

Pluto's unruly moons

GMT 13:12 2015 Saturday ,09 May

Sheikh Sultan opens Sharjah Centre

GMT 15:43 2017 Wednesday ,17 May

Nada Hassan talks about basic ways for skin care
Arab Today, arab today
Arab Today, arab today
 
 Arab Today Facebook,arab today facebook  Arab Today Twitter,arab today twitter Arab Today Rss,arab today rss  Arab Today Youtube,arab today youtube  Arab Today Youtube,arab today youtube
arabstoday arabstoday arabstoday arabstoday
arabstoday arabstoday arabstoday
arabstoday
بناية النخيل - رأس النبع _ خلف السفارة الفرنسية _بيروت - لبنان
arabstoday, Arabstoday, Arabstoday