Arab Today, arab today bioinspired nanococoons offer a new way
Last Updated : GMT 06:04:29
Arab Today, arab today
Arab Today, arab today

Bio-inspired nano-cocoons offer a new way

Arab Today, arab today

Arab Today, arab today Bio-inspired nano-cocoons offer a new way

National Cancer Institute (NCI)
New York - Arab Today

In the U.S. alone, the National Cancer Institute (NCI), created by the Nixon administration more than 40 years ago to help fight the war, has spent nearly $100-billion in funding, with hundreds of millions more raised and spent by cancer charities and hospital foundations.
There are constant disputes on whether money is being wasted on researches that fail or don't necessarily require that much of a big amount. At the end, we can't put a price limitation on our lives and even if we fail, at least we are getting closer to ending the battle with cancer. An outgoing study is set to be the change we have been looking for.
The research consists of bio-inspired nano-cocoons and offers the newest method for delivering drugs used to treat the spread of cancer cells. Drug delivery, being the most crucial pharmaceutical application, is the most focused area in nanobiotechnology.
Nanobiotechnology is considered by many as the most promising technology of the 21st century with numerous new important applications in medicine and is poised for an indefinite period of healthy growth. According to GIA (The Gemological Institute of America), global market for Nanobiotechnology is projected to reach US$6.0 billion by the year 2017.
The commercial applications of nanobiotechnology in biomedical field are principally directed towards development of novel drug delivery systems, and the trend is likely to remain intact for several years to come.
Current treatments for cancer vary depending on a number of factors: the type of cancer a person has, what stage the cancer is in and the person’s age or health status. Doctors typically rely on a number of different types of therapy and palliative care. Current treatment options include surgery, chemotherapy, hormone therapy, gene therapy, radiation and immunotherapy. The use of bio-inspired nano-cocoons would fall under the category of immunotherapy.
The research is conducted by scientists located at North Carolina State University and the University of North Carolina at Chapel Hill. Co-authors on the research project for these bio-inspired nano-cocoons include three Ph.D. students: Yue Lu, Margaret Reiff, and Tianyue Jiang and Dr. Ran Mo, a former postdoctoral biomedical engineering researcher.
Each bio-engineered cocoon consists of a single DNA strand that manipulates itself into the shape of a ball of yarn measuring 150 nanometers wide. They can carry large amounts of anti-cancer drugs and release them rapidly into the cancer cells once inside.
The nano-cocoons are less toxic to patients than other systems which use synthetic materials. They are also easier to manufacture because scientists built them with a self-assembling nature.
The core of the cocoon stores a anticancer medicine called doxorubicin (DOX) and a protein enzyme known as DNase. The DNase enzyme is coated with a layer of thin polymer to prevent it from slicing open the cocoon prematurely. The surface of the cocoon is peppered with folic acid molecules known as ligands that binds it to receptors located on cancer cells and force the cells to suck the nano-cocoon inside. The cancer cell’s acidic environment then rips apart the polymer coating containing the DNase enzyme and thereby unleashes the doxorubicin that kills the cell.
"In addition, because we used self-assembling DNA techniques, it is relatively easy to manufacture," says Wujin Sun, lead author of the paper “Cocoon-Like Self-Degradable DNA-Nanoclew for Anticancer Drug Delivery” and a Ph. D student in Gu's lab.
Gu says: "We're very excited about this system and think it holds promise for delivering a variety of drugs targeting cancer and other diseases. This technique also specifically targets cancer cells, can carry a large drug load and releases the drugs very quickly once inside the cancer cell."
The great volume of knowledge accumulated about cancer over the years is one of science’s great accomplishments, however many believe that widespread cures won't happen until our children’s time on earth, expecting a series of small advances and no dramatic breakthroughs. But isn't that the kind of a future we are all hoping for?

 

Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

Arab Today, arab today bioinspired nanococoons offer a new way Arab Today, arab today bioinspired nanococoons offer a new way

 



Arab Today, arab today
Arab Today, arab today Jordan airline suggests flyers 'talk'

GMT 11:59 2017 Friday ,24 March

Jordan airline suggests flyers 'talk'
Arab Today, arab today 5 Crafty Must-Have Limited-Budget Ideas

GMT 17:03 2017 Saturday ,25 March

5 Crafty Must-Have Limited-Budget Ideas
Arab Today, arab today Rebel supporters flood Yemen streets

GMT 06:39 2017 Monday ,27 March

Rebel supporters flood Yemen streets
View News in Arabic - Culture: مراجعة كتب
Arab Today, arab today
Arab Today, arab today
Arab Today, arab today Yemen children dream of school

GMT 07:25 2017 Friday ,24 March

Yemen children dream of school
Arab Today, arab today Trump to roll back Obama clean power plan

GMT 11:10 2017 Monday ,27 March

Trump to roll back Obama clean power plan
Arab Today, arab today Prepares to give stargazers an eyeful

GMT 13:38 2017 Monday ,06 March

Prepares to give stargazers an eyeful
Arab Today, arab today Uber grounds self-driving cars

GMT 09:11 2017 Monday ,27 March

Uber grounds self-driving cars
Arab Today, arab today Audi RS 5 Coupe acquires new design

GMT 13:22 2017 Thursday ,23 March

Audi RS 5 Coupe acquires new design
Arab Today, arab today Nermein Al Fekki films “Foxes in the Valley”

GMT 09:58 2017 Saturday ,25 March

Nermein Al Fekki films “Foxes in the Valley”
Arab Today, arab today Salvage of South Korea's Sewol ferry

GMT 04:51 2017 Friday ,24 March

Salvage of South Korea's Sewol ferry

GMT 06:21 2017 Friday ,24 March

MP submits a petition to dismiss university head

GMT 18:57 2017 Tuesday ,21 March

Accessories designer reveals her new collection

GMT 15:25 2017 Tuesday ,21 March

2017 already marked

GMT 13:26 2017 Friday ,24 February

Expresses Algerian history by woody figures

GMT 20:03 2017 Saturday ,25 March

Health expert warns from dust sensitivity

GMT 07:36 2017 Wednesday ,22 March

US, Britain ban laptops on flights

GMT 06:31 2015 Thursday ,04 June

Pluto's unruly moons

GMT 06:04 2017 Tuesday ,28 March

Saudi Arabia ranks 3rd globally for smartphone use

GMT 19:27 2017 Saturday ,11 March

Boualsof launches "Priestess Kahina" collection
Arab Today, arab today
Arab Today, arab today
 
 Arab Today Facebook,arab today facebook  Arab Today Twitter,arab today twitter Arab Today Rss,arab today rss  Arab Today Youtube,arab today youtube  Arab Today Youtube,arab today youtube
arabstoday arabstoday arabstoday arabstoday
arabstoday arabstoday arabstoday
arabstoday
بناية النخيل - رأس النبع _ خلف السفارة الفرنسية _بيروت - لبنان
arabstoday, Arabstoday, Arabstoday