Former Coronation Street star Julie Hesmondhalgh is up for best soap actress at the TV Choice Awards.
The actress, who portrayed long-running character Hayley Cropper's death from cancer on the ITV show, is up against EastEnders' Lindsay Coulson.
Coulson's character Carol Jackson has breast cancer in the BBC One soap.
BBC One's Sherlock star Benedict Cumberbatch is up for best actor, while the show faces the channel's Waterloo Road and ITV's Downton Abbey.
BBC One's Call The Midwife completes the shortlist for best drama. The 1950s period piece has also picked up a best actress nomination for Judy Parfitt, who plays ageing nun Sister Monica Joan in the programme.
People can vote on the TV Choice website until Friday 18 July.
In the best entertainment show category, perennial nominees Ant and Dec's Saturday Takeaway on ITV and The Graham Norton Show on BBC One will do battle against one another.
Returning sitcom Birds of a Feather is in the running for best comedy. The Essex show returned to screens after a 15-year hiatus, and proved to be a ratings success for ITV, having originated on the BBC.
Elsewhere in the soap categories, new EastEnders clan the Carters have picked up a trio of nominations, including Danny Dyer, who plays landlord of the Queen Vic, Mick Carter.
Two of his children, played by Maddy Hill and Sam Strike, are in the frame for best newcomer.
Hesmondhalgh, who played Hayley Cropper for 16 years, won a National Television Award in January for her role.